Zhongchao Kevin Zhao
Education and Training
2020 - present
Postdoc in NanoEngineering
University of California, San Diego
2014 - 2020
Ph.D. in Biochemistry
Indiana University
2011 - 2014
Master in Biochemical Engineering
Chinese Mining and Technology-Beijing
Chinese Academy of Agricultural Sciences
2007 - 2011
Bachelor in Bioengineering
Chinese Mining and Technology-Beijing
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Bioprinting hydrogel with cowpea mosaic virus for ovarian cancer treatment.
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Designing and developing in-situ cancer immunotherapy using liposome and cowpea mosaic virus for ovarian cancer treatment
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Developed personalized cancer vaccine to prevent ovarian cancer recurrence by combining cowpea mosaic virus with irradiated cancer cells.
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Developed tobacco mosaic virus as chemotherapeutic drug carrier for ovarian cancer treatment.
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Characterized the effects of hydrophobicity-hydrophilicity of molecular polymer bottlebrushes on tumor homing.
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Re-engineered a heterodimer that directs new assembly pathways to form intermediates and holey capsids.
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Identified a pair of charged residues that allosterically regulate capsid assembly through secondary and quaternary structures.
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Determined the dimer and capsid structures of Woodchuck Hepatitis virus and compared them to HBV structures to reveal a structural progression during the capsid assembly.
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Using bioinformatic analysis, identified a putative gene cluster that is responsive to copper homeostasis in the bacterium Deinocuccus radiodurans R1.
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Using genetic mutations, developed two bacteria mutants and tested their resistance in response to copper and oxidative stresses.
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Using RT-PCR and DNase I footprinting approaches, confirmed the functions of the genes and their corresponding proteins upon copper stimulation.
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Using molecular biology, cloned and characterized two P1B-ATPase genes, BjHMA2/4, that are involved in transporting heavy metal in the plant Brassica juncea